<b>Demonstration of a 72 K β-protein precursor fragment in Alzheimer and normal aged </b><b>brain </b>

α-Secretase processing of the Alzheimer amyloid-β precursor protein and its homolog APLP2

The E1 domain of APP and APLP2 determines α-secretase specificity Manuscript 6 Additional publications  Jacobsen KT and Iverfeldt K Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors Exposure to the saturated free fatty acid palmitate alters BV-2 microglia inflammatory response Abstract The amyloid-β precursor protein (APP) has been widely studied due to ...

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

: the effect of sericin levels (silk glue protein) on rate of in vitro maturation, fertilization and culture of sheep oocytes

هدف از آزمایش اول بررسی اثر سطوح مختلف سریسین [0 (control), 0.1, 0.5, 1.0, 2.5 %] افزوده شده به محیط , ivm بر cumulus cell expansion، بلوغ هسته و توسعه متوالی جنین، در گوسفندان نژاد سنجابی در فصل تولید مثلی می باشد. از سرگیری میوز به وسیله خارج شدن اولین پولار بادی اندازه گیری و هم چنین درصد رسیدن جنین های دو سلولی به مرحله کلیواژ و بلاستوسیت نیز به عنوان نشانه ای از میزان شایستگی توسعه اولیه ج...

Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.

Development of disease-modifying therapeutics is urgently needed for treating Alzheimer disease (AD). AD is characterized by toxic β-amyloid (Aβ) peptides produced by β- and γ-secretase-mediated cleavage of the amyloid precursor protein (APP). β-secretase inhibitors reduce Aβ levels, but mechanism-based side effects arise because they also inhibit β-cleavage of non-amyloid substrates like Neure...

Mechanism of Alzheimer Amyloid β-Protein Precursor Localization to Membrane Lipid Rafts